Cy-fbp/sbpase

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August undefined, 2024

WebIn the present study, we targeted the substrate binding pocket of cy-FBP/SBPase. A series of novel hit compounds from the SPECs database were selected by using a pharmacophore-based virtual screening strategy. Most of the compounds tested exhibited moderate inhibitory activities (IC50 = 20.7–176.9 μM) against cy-FBP/SBPase. WebJan 1, 2024 · To investigate if increased SBPase activity will increase yield in soybean under future climate, we grew WT and FBP/SBPase-expressing (FS) plants side by side under ambient and elevated [CO 2] (400 μmol mol −1 and 600 μmol mol −1, respectively) combined with canopy heating of +2.7 °C during the day and +3.4 °C at night. The full ...

sedoheptulose-1,7-bisphosphatase. - PDF Download Free

Web(2014) Feng et al. FEBS Journal. Cyanobacterial fructose-1,6/sedoheptulose-1,7-bisphosphatase (cy-FBP/SBPase) plays a vital role in gluconeogenesis and in the ... WebMar 24, 2014 · Cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphoshatase (cy-FBP/SBPase) is a potential enzymatic target for screening of novel inhibitors that can … philip morris intl inc stock

Structural and biochemical characterization of fructose-1

WebTransfer data for use with other programs, for example, with a spreadsheet program. The general steps to transfer data are: Use bcp to move the data from Adaptive Server into … Web16 Cyanobacteria fructose-1, 6-/sedoheptanose-1, 7-diphosphatase (Cy-FBP/SBPase) is 17 an essential regulatory enzyme in cyanobacterial photosynthesis and a potential target … WebIn the present study, we targeted the substrate binding pocket of cy-FBP/SBPase. A series of novel hit compounds from the SPECs database were selected by using a pharmacophore-based virtual screening strategy. Most of the compounds tested exhibited moderate inhibitory activities (IC50 = 20.7-176.9 μM) against cy-FBP/SBPase. philip morris italia bologna

Overexpression of a cyanobacterial fructose-1,6-/sedoheptulose-1, 7

Contribution of Fructose-1,6-bisphosphatase and Sedoheptulose …

WebEnzymatic analysis showed that the T compounds had little inhibitory effect on Cy-FBP/SBPase (Table S1). Interestingly, the compounds T2-T7 showed better algal-inhibition than L1, suggesting that they may act on other target enzymes or have other novel mechanisms of actions. WebThe interactions between ligands and cy–FBP/SBPase are different from those of ligand‐bound structures of other FBPase family members, and thus provide new insight into the molecular mechanisms of structure and catalysis of cy–FBP/SBPase. Our studies provide insight into the evolution of this enzyme family, and may help in the design of ... philip morris invests in chronsWebWe identified a series of residues important for FBP and AMP binding, and suggest formation of a disulfide linkage between Cys75 and Cys99. Further analysis indicates … philip morris investing

"WebOct 1, 1996 · In addition to this enzyme, cyanobacteria also possess a unique enzyme, fructose-1,6-/sedoheptulose-1,7-bisphosphatase (FBP/SBPase), that can hydrolyze both FBP and SBP (Tamoi et al., 1996). A similar enzyme that hydrolyzes both FBP and SBP has been isolated from spinach leaves (Gontero et al., 1984a,b). Show abstract " - Cy-fbp/sbpase

Cy-fbp/sbpase

WebOct 1, 2001 · The FBPase activity derived from plastidic and cytosolic FBPase and cyanobacterial FBP/SBPase in TpFS-3 and TpFS-6 was 1.8 ± 0.2 and 1.3 ± 0.1 μmol/mg chlorophyll/min, respectively. Plastidic... WebMar 1, 2006 · We have demonstrated that transgenic tobacco (TpFS) plants expressing cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase (FBP/SBPase) in chloroplasts exhibit increased photosynthetic CO 2 fixation capacity and final dry matter under atmospheric conditions (360 ppm CO 2) ( Miyagawa et al. 2001 ).

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WebCACYBP. Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene. [5] [6] [7] The protein encoded by this gene is a calcyclin binding protein. It may be … WebTo change the setting of the CICS SIT table property, ask the CICS system programmer and the external security manager. The SIT property defines the intersystem refresh delay, …

WebWe describe the crystal structure of cy‐FBP/SBPase +AMP+FBP, which is dynamic and harbors at least three regulatory domains. The state of cy‐FBP/SBPase is changed among three potential states in the presence of different regulators: initial non‐active dimer state, non‐active tetramer state and active tetramer state. In the non‐active dimer state, a … WebNov 29, 2013 · cy–FBP/SBPase exhibits unique biochemical characteristics compared with previously characterized FBPase enzymes. It has a wider substrate range and …

WebMay 25, 2016 · In Pp SBPase, a β-hairpin is formed in the α2–α4 loop containing Cys120 and Cys125 instead of helix α3 in Pp FBPase. In Pp FBPase, the β4–β5 loop containing Cys224 and Cys241 is extended with respect to the corresponding loop in Pp SBPase by 22 amino acids (34 vs. 12 residues). WebIn this article, we have altered the levels of three different enzymes involved in the Calvin-Benson cycle and photorespiratory pathway. We have generated transgenic Arabidopsis plants with altered combinations of sedoheptulose 1,7-bisphosphatase (SBPase), fructose 1,6-bisphophate aldolase (FBPA) and the glycine decarboxylase-H protein (GDC-H) …

WebMay 25, 2016 · In chloroplasts, the activity of four enzymes of the cycle is linked to light: NADP-glyceraldehyde 3-phosphate dehydrogenase, phosphoribulokinase, fructose-1,6 … philip morris japan addressWebSep 2, 2016 · Sedoheptulose-1, 7-bisphosphatase (SBPase) is an important enzyme involved in photosynthetic carbon fixation in the Calvin cycle. Here, we report the impact of changes in SBPase activity on... tru hotel salt lake city utWebThe invention provides a chromone-containing benzimidazole bifurazan compound with a Cy-FBP/SBPase inhibition effect and a preparation method of the chromone-containing benzimidazole bifurazan compound. The molecular structure of the compound is shown as tru hotels by hilton waco txWebIn the present study, we targeted the substrate binding pocket of cy-FBP/SBPase. A series of novel hit compounds from the SPECs database were selected by using a pharmacophore-based virtual screening strategy. Most of the compounds tested exhibited moderate inhibitory activities (IC50 = 20.7−176.9 μM) against cy-FBP/SBPase. tru hotels by hilton columbia scWebJul 22, 2024 · FBAase and SBPase are two key enzymes in regeneration of RuBP. FBAase catalyzes two reactions: one is the conversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP) … philip morris japan careerWebMar 16, 2024 · A novel variant of the Calvin-Benson cycle bypassing fructose bisphosphate Sci Rep. 2024 Mar 16;12 (1):3984. doi: 10.1038/s41598-022-07836-7. Author Jun Ohta 1 Affiliation 1 Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikatacho, Kita-ku, Okayama, 700-8558, Japan. [email protected] … tru hotel shuttleWebJun 1, 2013 · In this study, as potential inhibitors of Cy-FBP/SBPase, a series of novel chromone-connecting benzohydrazone compounds (Novel N′-((4-oxo-4H-chromen-3 … tru hotel rockwall tx