WebSep 17, 2024 · For the entire ITT population, the 3-year PFS was numerically higher in the dd-MVAC arm than in the GC arm — 64% and 56%, respectively — but the difference … WebResults of the 2-week-per-cycle regimen were compared with classic MVAC (4 weeks per cycle) and gemcitabine/cisplatin (GC, 3 weeks per cycle). Methods: We included 166 patients with non-organ-confined MIBC, who received neoadjuvant induction dd-MVAC (80), classic MVAC (35), or GC (51) between 1990 and 2014. Complete pathological response …
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WebAug 7, 2024 · The pT0 rates were 32% for ddMVAC and 35% for GC, whereas the ≤pT1 rates were 55% and 49%, respectively. 44 Of note, this study was designed to explore the utility of gene expression-based biomarkers for pCR prediction in patients receiving NAC and did not directly compare these 2 regimens. In a more recent report, the … WebJun 2, 2024 · The effects of ddMVAC and GC on OS and CSS were assessed by pooled HRs and 95% CIs . Between-study heterogeneity was assessed using chi-square and I 2 tests. A Cochran Q statistic p-value < 0.05 or I 2 statistic >50% was used to indicate statistically significant heterogeneity between trials . tactical battery storage case
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WebSep 21, 2016 · In the GC arm, gemcitabine doses on day 8 or 15 were omitted for WBC ≤ 1.99 × 10 9 /L and platelets ≤ 49 × 10 9 /L. In the MVAC arm, methotrexate or vinblastine … WebDec 1, 2024 · This trial randomized 237 patients between NAC with ddMVAC and GC. The comparison of CR rates between the two regimens was a secondary endpoint in this trial demonstrating no significant difference with CR rates for ddMVAC at 28% versus GC at 30%. These results were supported by the VESPER trial which also failed to note a … WebOct 1, 2024 · Cisplatin-based chemotherapy administered before cystectomy has demonstrated improved survival in MIBC. 11, 14, 22 Published data supports the use of GC or ddMVAC, and several retrospective studies have been published for various stages of MIBC using several perioperative chemotherapy modalities, but the lack of randomized … tactical beanie with velcro