Web24 Sep 2024 · Interstitial lung disease (ILD) is the leading cause of mortality in systemic sclerosis, a rare autoimmune disease characterised by fibrosis and vasculopathy. ... Hague CJ, Leipsic J, et al. Predictors of mortality and progression in scleroderma-associated interstitial lung disease: a systematic review. Chest. 2014;146(2):422–36. Article ... INTRODUCTION Interstitial lung disease (ILD) is a frequent complication of systemic sclerosis (SSc) that is often progressive and has a poor prognosis [1-7]. SSc-associated ILD consists of various histopathologic subtypes, most commonly nonspecific interstitial pneumonitis and usual interstitial … See more TYPES OF INTERSTITIAL LUNG DISEASE The term interstitial lung disease (ILD) is broadly used to describe a heterogeneous group of disorders that are classified together because of similar clinical, radiographic, … See more It is thought that patients are more likely to benefit from therapy when it is initiated early in the course of disease, before a substantial loss of lung function has occurred [12-16]. In … See more A minority of patients with SSc-ILD have the histopathologic pattern of UIP [8], the characteristic pattern associated with idiopathic pulmonary fibrosis (IPF). This pattern is … See more INITIATING THERAPY The optimal treatment for systemic sclerosis-associated interstitial lung disease (SSc-ILD) is not known. Based on the best available evidence, we suggest initiating immunosuppressive … See more
CIRP, stress-response protein, levels high in SSc-ILD patients
Web25 Mar 2024 · Systemic sclerosis, also known as scleroderma, is an autoimmune disease associated with fibrosis of the skin and other organs. Interstitial lung disease (ILD) can … Web11 Apr 2024 · Systemic sclerosis (SSc; scleroderma) is a relatively rare disease whose pathogenesis is characterized by 3 hallmarks: small vessel vasculopathy, production of autoantibodies, and fibroblast dysfunction leading to increased deposition of extracellular matrix. ... Does Systemic Sclerosis-associated Interstitial Lung Disease Burn Out? … roush door sills
Scleroderma (pulmonary manifestations) - Radiopaedia
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