http://tools.iedb.org/main/bcell/ WebOct 9, 2024 · A comprehensive database of curated and well-annotated BCR transcripts, should therefore accelerate repertoire studies including but not limited to characterization of B cell receptor diversity, mechanisms of clonal expansion, development of BCR repertoire analysis algorithms, estimation of frequency of antigen-specific antibodies and their …
Frontiers cAb-Rep: A Database of Curated Antibody Repertoires …
WebComplete immune repertoire Paired, full-length Ig sequence, including isotypes, and T-cell receptor α/β. Immune mapping Map antigens to discover novel antigen-specific Ig or T-cell receptors. Streamlined data analysis Explore and visualize clonotype information with easy-to-use software. One-day lab workflow WebAntigen-specific T cells play a central role in the adaptive immune response and come in a wide range of phenotypes. T cell receptors (TCRs) mediate the antigen-specificities found in T cells. Importantly, high-throughput TCR sequencing provides a fingerprint which allows tracking of specific T cells and their clonal expansion in response to particular antigens. … hagerstown museum of art
Frontiers The Cancer Epitope Database and Analysis Resource: …
WebAug 11, 2016 · We present a public database of more than 37 million unique BCR sequences from three healthy adult donors that is many fold deeper than any existing resource, together with a set of online tools designed to facilitate the visualization and analysis of the annotated data. WebMar 24, 2024 · PD-1 is expressed on activated T and B cells, natural killer (NK) cells, monocytes, dendritic cells, and cancer cells such as melanoma. Because in lymphocytes triggering TCR and BCR induces PD-1 expression, PD-1 is generally considered to downmodulate the activity of antigen-experienced T and B cells . PD-1 is activated by … WebApr 13, 2024 · BCR and TCR libraries were sequenced at a target depth of 5,000 reads per cell. Raw scRNA-seq reads were mapped with cellranger 3.0.2 with Ensembl 93-based GRCh38 reference. hagerstown parks and recreation department